Although symbols themselves are case-sensitive (you can create uppercase and lowercase symbols via string->symbol), by R5RS the standard required the reader to effectively fold the cases when it is reading symbol, so that 'a and 'A are treated as eq?
Almost all active implementations, however, have a switch to choose case-sensitiveness of the symbol reader. Furthermore, more and more recent implementations seem to adopt case-sensitive reader by default.
Here's a list of implementations and their default case sensitivity ('S' for sensitive, 'I' for insensitive), and whether they have an option to switch. (If you want to add or correct entries, please go ahead.)
(* Pocket Scheme: only folds case between U+0000 - U+00FF)
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